The FDA has released draft guidance on how sponsors can use Bayesian models for clinical trials.

In this video interview, David Morton, PhD, director of biostatistics at Certara, reflects on the growing role of Bayesian approaches in modern drug development, emphasizing their potential to improve ...

Empirical Bayes is a versatile approach to “learn from a lot” in two ways: first, from a large number of variables and, second, from a potentially large amount of prior information, for example, ...

We review Bayesian and Bayesian decision theoretic approaches to subgroup analysis and applications to subgroup-based adaptive clinical trial designs. Subgroup analysis refers to inference about ...

In this video interview, David Morton, PhD, director of biostatistics at Certara, explains how regulatory momentum is ...

Brazilian Journal of Probability and Statistics, Vol. 27, No. 1 (February 2013), pp. 1-19 (19 pages) We introduce a Bayesian analysis for beta generalized distributions and related exponentiated ...