Protein imaging has become a central approach for understanding how proteins function within complex biological systems. Advances in protein imaging techniques now allow researchers to visualize ...

Tumour cells can be stably transfected with fluorescent proteins. Tumours and metastases that express fluorescent proteins can be visualized non-invasively in intact animals. Transgenic mice can ...

CluMPS—Clusters Magnified by Phase Separation—is a fluorescent reporter strategy for detecting protein clusters. It promises to facilitate the visualization of protein clusters that are too small to ...

Inside a living cell, proteins and other molecules are often tightly packed together. These dense clusters can be difficult to image because the fluorescent labels used to make them visible can't ...

The genome contains all of the instructions a cell needs to build an organism. In coding regions of the genome, genes are transcribed into a molecule called mRNA, which is processed and then ...

A team of researchers has revealed that the Dumpy protein, a component of extracellular matrices -- or ECM -- is the key factor in regulating the stereotypic origami-like folding of wing-cell sheets.

Each one of the trillions of cells that make up the human body suffers more than 10,000 DNA lesions every day. These injuries would be catastrophic if cells were unable to repair them, but a very ...

A novel reporter protein has been developed to enable the investigation of protein biogenesis in the ER and its disruption in disease. A recent research collaboration between multiple Japanese ...

Protein blotting enables both exploratory research and standardized validation of new antibodies and other protein detection assays. Blotting methods are staples across many laboratories, and the ...