Pulmonary arterial hypertension (PAH) involves progressive cellular and molecular change within the pulmonary vasculature, leading to increased vascular resistance. Current therapies targeting nitric ...

The origin of many diseases begins at the cellular level and involves multiple molecular interactions. However, previous methods have struggled to accurately observe changes in individual cells.

AGBT is also, increasingly, a showcase for instruments for spatial biology, a fast-growing field that involves pinpointing the location of RNA and protein molecules en masse. Tarbox calls the meeting ...

Breast cancer remains one of the most prevalent and life-threatening forms of cancer, impacting millions worldwide. This malignancy's heterogeneity and complexity have long posed significant ...

The country’s first end-to-end workflow unites IRB Barcelona’s core facilities to support spatial omics for researchers, ...

Advancements in spatial perturbation transcriptomics (SPT) have revolutionized our understanding of cellular behavior in native tissue contexts by integrating spatial and perturbation data. However, ...

The HALP score as a prognostic biomarker in non-small cell lung cancer: A comprehensive meta-analysis of over 7,000 patients. This is an ASCO Meeting Abstract from the 2025 ASCO Annual Meeting I. This ...

aDepartment of Genetic and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA bDivision of Molecular Psychiatry, Department of Psychiatry, Yale University School of Medicine, ...

Abstract: Spatial transcriptomics has revolutionized the ability to investigate transcriptional patterns within tissue morphology. However, many ST clustering pipelines operate on a single preselected ...

The rapid development of spatial transcriptomics (ST) technologies has greatly advanced the understanding of gene expression, tissue architecture, cellular composition, and disease mechanisms within ...