AML1–ETO downregulates the granulocytic differentiation factor C/EBPα in t(8;21) myeloid leukemia
Figure 3: Conditional expression of AML1-ETO downregulates CEBPA expression and inhibits C/EBPα function. Figure 4: AML1–ETO inhibits CEBPA autoregulation in myeloid cells. Figure 5: Restoration of ...
In mammalian cells, apoptosis is modulated by two protein families — the BCL2 and inhibitor of apoptosis (IAP) families. Survivin is a unique member of the IAP family. It is associated with several ...
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